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ⓘ Formyltetrahydrofolate dehydrogenase. In enzymology, a formyltetrahydrofolate dehydrogenase is an enzyme that catalyzes the chemical reaction 10-formyltetrahydr ..



                                     

ⓘ Formyltetrahydrofolate dehydrogenase

In enzymology, a formyltetrahydrofolate dehydrogenase is an enzyme that catalyzes the chemical reaction

10-formyltetrahydrofolate + NADP + + H 2 O ⇌ {\displaystyle \rightleftharpoons } tetrahydrofolate + CO 2 + NADPH + H +

The 3 substrates of this enzyme are 10-formyltetrahydrofolate, NADP +, and H 2 O, whereas its 4 products are tetrahydrofolate, CO 2, NADPH, and H +.

This enzyme belongs to the family of oxidoreductases, to be specific those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-formyltetrahydrofolate:NADP+ oxidoreductase. Other names in common use include 10-formyl tetrahydrofolate:NADP oxidoreductase, 10-formyl-H2PtGlu:NADP oxidoreductase, 10-formyl-H4folate dehydrogenase, N10-formyltetrahydrofolate dehydrogenase, and 10-formyltetrahydrofolate dehydrogenase. This enzyme participates in one carbon pool by folate.

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