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ⓘ Chondroitin AC lyase. In enzymology, a chondroitin AC lyase is an enzyme that catalyzes the chemical reaction Eliminative degradation of polysaccharides contain ..



                                     

ⓘ Chondroitin AC lyase

In enzymology, a chondroitin AC lyase is an enzyme that catalyzes the chemical reaction

Eliminative degradation of polysaccharides containing 1.4-beta-D-hexosaminyl and 1.3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is chondroitin AC lyase. Other names in common use include chondroitinase ambiguous, chondroitin sulfate lyase, chondroitin AC eliminase, chondroitin AC lyase, chondroitinase AC, and ChnAC.

                                     

1. Structural studies

As of late 2007, 11 structures have been solved for this class of enzymes, with PDB accession codes 1CB8, 1HM2, 1HM3, 1HMU, 1HMW, 1RW9, 1RWA, 1RWC, 1RWF, 1RWG, and 1RWH.

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