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ⓘ Formimidoylglutamase. In enzymology, a formimidoylglutamase is an enzyme that catalyzes the chemical reaction N-formimidoyl-L-glutamate + H 2 O ⇌ {\displaystyle ..



                                     

ⓘ Formimidoylglutamase

In enzymology, a formimidoylglutamase is an enzyme that catalyzes the chemical reaction

N-formimidoyl-L-glutamate + H 2 O ⇌ {\displaystyle \rightleftharpoons } L-glutamate + formamide

Thus, the two substrates of this enzyme are N-formimidoyl-L-glutamate and H 2 O, whereas its two products are L-glutamate and formamide.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is N-formimidoyl-L-glutamate formimidoylhydrolase. Other names in common use include formiminoglutamase, N-formiminoglutamate hydrolase, and N-formimino-L-glutamate formiminohydrolase. This enzyme participates in histidine metabolism.

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